Daily calorie intake and efficacy of 24-hours blood pressure control in hypertensive patients with obesity on stable antihypertensive therapy

Abstract Although it has been established that excessive daily calorie intake contributes to the development of hypertension, relation between energy consumption and blood pressure in patients on stable antihypertensive therapy is not yet known. The aim study was evaluate 24 hours control therapy. Materials methods Cross-sectional included 141 hypertensive with age median 56.5 (45.00 ÷ 63.70) years old. All had during three months target office at moment inclusion study. Ambulatory monitoring (ABPM) done all Heaco ABPM50 monitoring. Physical activity assessed using International Activity Questionnaire (kcal/week). Patients full dietary diaries mean for days calculated standardized soft “Test Rational Nutrition” (TRP-D02, Ukraine). Fasting glucose, HbA1c, lipids, uric acids, creatinine, C-reactive protein were patients. Data analyzed SPSS IBM 19.0. Results Mean systolic (SBP) 128.5±11.3 mmHg diastolic (DBP) 78.5±9.1 mmHg; body mass index (BMI) 34.7±6.2 kg/m2. divided into groups according intake: 1st group (n=21) intook less than 1372.2 kcal per day, 2nd (n=58) 1373.2 2976.3 day 3rd (n=62) subjects more 2977.5 day. Body 1, 2 3 corresponds 30.34±5.1, 35.1±8.9 34.3±6.9 kg/m2, ANOVA test F=2.3, p=0.10. physical level low did differs significantly groups. ambulatory are presented table 1. It observed high non-satisfactory ABPM. odd ratio SBP higher 1.21 (95% CI, 0.42–4.51) 2.67 0.67–11.70). DBP 1.19 0.33–3.50) 2.12 0.61–7.79). night 2.81 0.33–10.51) 2.88 0.37–9.43). Conclusion In obesity control. Funding Acknowledgement Type funding sources: Public grant(s) – National budget only. Main source(s): Academy Medical Science Ukraine